Infectious Diseases and Clinical Microbiology
Inside Turkey’s infectious disease and clinical microbiology network that few ever see
Biruni Hospital’s Infectious Diseases and Clinical Microbiology Department specializes in the diagnosis, treatment, and prevention of infections. Using advanced laboratory techniques, our experts manage bacterial, viral, and parasitic diseases with precision and care.

Infectious diseases and clinical microbiology shape much of what modern healthcare faces today. Biruni Hospital has put real effort into staying ahead in these areas. Detecting infections early and tackling microbial resistance takes steady focus and expertise. Problems don’t wait and neither does good care. .
What is infectious diseases and clinical microbiology ?
Infectious diseases and clinical microbiology are about figuring out what bugs are making people sick and how to stop them, it’s not just running tests but making sense of them to help doctors choose the right treatment.
This work happens behind the scenes in labs and at the bedside, aiming to catch infections early and keep them from spreading. It’s a mix of science and practical know-how that drives real decisions in hospitals and clinics.
Key parts of what this involves
- Pinpointing the exact germ using lab tools and tests
- Making sense of lab results so doctors can act smart
- Tracking which germs are no longer responding to antibiotics
- Setting up rules to stop infections from jumping between patients
- Working with different specialists when infections get complicated
- Helping decide who needs vaccines and how to prevent outbreaks
- Studying new infections and better ways to detect them
What are the types of infectious diseases and clinical microbiology procedures ?
Infectious diseases and clinical microbiology procedures include a variety of diagnostic and monitoring techniques. Common types are blood cultures, urine and stool tests, throat and wound swabs, PCR testing, and serological tests for detecting viruses, bacteria, and parasites. These procedures help identify infections, guide treatment, and monitor response to therapy.
Culture and sensitivity testing
Culture and sensitivity testing is where you take samples from patients like blood sputum or urine and try to grow the exact bug causing the problem. This process isn’t fast since some germs take time to grow. But it gives doctors the real answer on what they’re dealing with and which antibiotics will work or fail.
It’s the kind of test that takes the guesswork out of treatment and stops doctors from shooting in the dark.
Steps and aspects of culture and sensitivity testing
- Collecting samples carefully to avoid contamination.
- Putting samples on special media that help bacteria or fungi grow.
- Waiting for colonies to appear which can take hours or days.
- Using tests to identify what kind of germ grew in the lab.
- Checking which antibiotics kill or stop the germ from growing.
- Reporting results clearly to doctors for treatment decisions.
- Following up with more tests if treatment isn’t working.
Molecular diagnostic testing
Molecular testing is about reading the genetic code of the infection instead of waiting for it to grow. It’s faster and picks up germs that don’t show up easily in regular tests. This matters when you need answers quickly like with viruses or tricky bacteria.
The lab looks for tiny pieces of DNA or RNA to confirm what’s causing the infection so doctors can act fast and smart.
Steps and aspects of molecular diagnostic testing
- Taking the right sample from the patient like a nasal swab or blood.
- Extracting genetic material carefully in the lab.
- Using techniques like PCR to amplify tiny amounts of DNA or RNA.
- Detecting the amplified genetic material through special machines.
- Interpreting the test to say if the infection is there or not.
- Running controls to make sure the test worked correctly.
- Combining test results with the patient’s symptoms for diagnosis.
Antimicrobial susceptibility testing
This test tells doctors which antibiotics or antifungal medicines will work best on the infection. It avoids wasted time on drugs that don’t work and helps slow down the spread of drug-resistant bugs.
The lab exposes the isolated germ to different medicines and sees which ones stop its growth. This info is vital to pick the right medicine and protect the patient from ineffective treatment.
Steps and aspects of antimicrobial susceptibility testing
- Growing the infection in a lab sample.
- Preparing standard amounts of bacteria for testing.
- Applying the bacteria to dishes with different antibiotics.
- Waiting to see which antibiotics stop the bacteria from growing.
- Measuring how much growth is prevented around each drug.
- Labeling the bacteria as sensitive, resistant or intermediate.
- Sending clear reports to doctors to guide treatment.
Serological testing
Serology looks at the patient’s blood to find antibodies or pieces of the germ itself. This helps detect infections when the bug is hard to find or when the body’s immune response gives the best clue.
Serology can show if the infection is new, old or if someone has built immunity. It’s especially useful for infections like hepatitis, HIV or parasites where direct detection is tricky.
Steps and aspects of serological testing
- Drawing blood samples carefully.
- Running tests like ELISA to find antibodies or antigens.
- Measuring how much antibody is present to judge the timing of infection.
- Comparing results to symptoms and exposure history.
- Retesting over time to watch how immunity changes.
- Using serology to screen donors or track outbreaks.
- Pairing serology with other tests for a full picture.
Infection control surveillance
This procedure watches how infections spread inside hospitals and clinics. It’s not just about reacting to cases but spotting patterns early so outbreaks don’t get out of hand.
Teams gather data and constantly check trends and recommend actions like isolation, better cleaning or limiting antibiotics. The goal is to keep patients safe and stop infections before they start spreading.
Steps and aspects of infection control surveillance
- Defining what counts as an infection based on clear rules.
- Collecting data from labs, patient files and observations.
- Watching for spikes or unusual infection clusters.
- Sharing findings quickly with hospital teams.
- Suggesting measures like hand hygiene or patient isolation.
- Checking if these measures reduce infections over time.
- Updating policies based on what’s working or not.
What are the preparations before infectious diseases and clinical microbiology procedures ?
Preparations before infectious diseases and clinical microbiology procedures depend on the type of test. Patients may need to fast, avoid certain medications, or provide samples like blood, urine, or stool in sterile containers. It’s important to follow all hygiene and collection instructions to ensure accurate results.
1. Patient history and symptom review
Everything starts with the basics, and that means listening to the patient. Their symptoms, how long things have been going on, what they’ve been exposed to recently, or where they’ve traveled.
All of that matters. It helps the team narrow down what could be causing the problem and avoids running tests that won’t lead anywhere. Sometimes the details people almost forget to mention turn out to be the most useful part of the diagnosis.
2. Sample type selection
This part is about choosing the right sample for the right situation. Not every infection shows up in blood, and not everything will be clear in a swab.
What the patient is feeling, where the symptoms are, and how long they’ve been there all affect which sample makes the most sense. Getting this step right saves time and gets answers quicker without backtracking.
3. Aseptic sample collection
When it’s time to collect the sample, nothing is left to chance. Everything has to be clean, precise, and done by the book. One mistake and you can end up with a result that doesn’t reflect what’s actually happening in the patient.
That’s why trained staff follow strict steps to make sure what goes into the lab is actually useful and not mixed with anything from the outside.
4. Labeling and documentation
Once the sample is taken, it needs to be clearly labeled with the patient’s info and matched with the clinical notes. The lab needs to know what they’re looking at and why, otherwise results lose their meaning.
It’s not just paperwork, it’s about giving the team a full picture so they can interpret the data with context, not guesswork.
5. Timely transport to the lab
Some samples lose value the longer they sit around. Certain germs start to break down while others grow too fast, which can ruin the accuracy of the results. That’s why samples need to get to the lab quickly and under the right conditions.
Whether it’s kept cold or put in a special container, the clock starts ticking as soon as it’s collected.
6. Communication with the lab
Sometimes it’s not enough to just send the sample and move on. A quick call or message between the clinician and the lab can make all the difference, especially if the case is complex or something unusual is suspected.
This helps the lab focus on what matters most and avoids wasting time on tests that won’t add value. It’s a small step but one that brings clarity fast.
7. Patient preparation and consent
In some situations, the patient needs to know what’s about to happen, especially if the sample involves something uncomfortable or invasive. Talking it through, answering questions, and getting clear consent not only respects the patient but also makes the process smoother.
Patients who understand what’s being done and why are more likely to stay calm and cooperate which helps everyone involved.
What happens during the post-procedure recovery period
Most people don’t think of recovery when it comes to tests or infectious disease treatments, but the body still goes through a lot. Even if there’s no surgery involved, whether it’s fighting off an infection, dealing with the side effects of strong medication or waiting for lab results to confirm things are truly improving, recovery has its own rhythm.
Short term healing period
- Feeling tired or off from antibiotics or antiviral meds
- Noticing symptoms easing off slowly as the infection clears
- Watching for any side effects like rash or stomach trouble
- Managing mild pain, fever, or swelling depending on the infection site
- Going to follow-up tests to make sure it’s really gone
- Cutting back on activity to let the body focus on healing
- Dealing with dehydration or stress from the illness
Long term healing period
- Taking time to rebuild strength after serious or long infections
- Doing more tests over weeks or months to catch signs of relapse
- Sticking to preventive meds if the infection tends to come back
- Getting support if the infection left physical damage or mobility issues
- Making lifestyle changes to avoid ending up in the same place again
- Rebalancing digestion after long antibiotic use
- Getting vaccines or boosters to fill the gap if immunity took a hit
Precision and timing
When it comes to infectious diseases and clinical microbiology, guessing has no place. What works is speed, accuracy and knowing exactly what you're dealing with before making a move.
From early sample collection to long-term recovery, every step matters. It's not dramatic. It's just the difference between getting better or missing what's really going on.
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